For dogs and cats
Flagyl (Metronidazole) is an antibiotic widely used to treat protozoan infections (e.g., Giardia, Entamoeba, Trichomonas, and/or Balantidium) in dogs, cats, or other domestic animals. It is also used for the treatment of chronic intestinal inflammatory diseases.
Veterinarians generally prescribe Flagyl for any anaerobic infection. Flagyl is a potent drug used to treat the following pathologies:
- Anaerobic infections that occur after whelping
- Malignant edema
- Cancer sores
- Necrotic mastitis
Veterinarians recommend Flagyl to treat the aforementioned diseases because most pets demonstrate high tolerance to this medication. In general, Flagyl is not harmful as it only affects protozoal infections. However, it is highly recommended that during treatment with Flagyl, concurrent administration of antihelminthic therapy and change in diet occur.
Flagyl is also available as an ointment or gel for skin problems caused by anaerobic microorganisms.
The use of Flagyl is not recommended when the following are present in a patient:
- Lactation period
- Liver failure
- Individual intolerance to the drug components
When diarrhea occurs, Flagyl should be administered in the following manner:
- Crush a half of the tablet into powder
- Add some water to the power and mix
- Feed it to a pet with a syringe without a needle
Flagyl is available in solution form for intravenous administration, which is recommended in severe and complicated cases. Such intravenous therapy should not be conducted for more than 3 days; after which there should be a switch to oral administration of tablets. Flagyl dosing is individual specific and should only be prescribed by a doctor.
Metronidazole is absorbed rapidly in the gastrointestinal tract of a dog or cat, reaching a maximum concentration after 1.5-2 hours. If Flagyl is administered with or immediately after food consumption absorption of Flagyl can be slowed.
Flagyl is metabolized by the liver and its active metabolites continue attacking the protozoal infection. After 6-8 hours, 50% of the active ingredient in Flagyl can be observed in plasma and nearly 80% is excreted within urine and/or feces. During the course of metabolism, skin pigmentation can develop and urine can turn a red-brown color.
For Flagyl use in cats and dogs, the dose of metronidazole is calculated based on weight. A typical dosage recommended for treating cats is 10 mg/kg, whereas for dogs it is 15-20 mg/kg. Flagyl should be administrated every 12 hours.